The Failure of Intracranial Pressure-volume Change
نویسنده
چکیده
A variety of lesions of the central nervous system may be associated with disturbances of renal function characterized by either the increased urinary loss of sodium and chloride (1-3) or the retention of salt (3-8). It has also been postulated that changes in the excretion of salt, secondary to alterations in the volume of blood or extracellular fluid, are mediated by a "volume receptor" located in the cranial cavity (9-12). The following experiments were therefore undertaken in order to investigate the influence of alterations in intracranial venous volume and pressure, and cerebrospinal fluid (CSF) volume and pressure on renal function.
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